Update: Police say the injuries are non-life threatening and that the highway is expected to be reopened by noon.
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One driver was transported to a trauma centre this morning following a collision between a car and a transport just before a second serious collision involving two commercial vehicles and a passenger van.
Both accidents happened west of the Highway 6 North exit to Guelph.
The Ontario Provincial Police Highway Division and Mississauga OPP said on X that one driver suffered serious injuries in the second collision and was taken to hospital by Ornge air ambulance. A second driver was transported to hospital by EMS.
All westbound lanes of the highway were closed at Guelph Line before 8 a.m.
Traffic is exiting at Hwy 6 north. Police have not stated when they expect the westbound lanes to reopen.