A crash involving two vehicles has closed Eramosa Road at Callander Drive, between Stevenson Street and Victoria Road.
Traffic is being diverted in both directions as emergency crews clean up the scene and police investigate.
The incident happened around 5 p.m.
It is not known if there were any injuries, although airbags were deployed.
This story will be updated.
Please avoid the area of Eramosa Road between Victoria Road North and Callander Drive in #Guelph. A serious motor vehicle collision has occurred and the road is closed in both directions while the investigation takes place. -KG pic.twitter.com/UF0clWLlaA
— Guelph Police Service (@GuelphPolice) August 24, 2022